Low price Pyrrolidine CAS 123-75-1 in stock
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Low price Pyrrolidine CAS 123-75-1 in stock
Low price Pyrrolidine CAS 123-75-1 in stock
Low price Pyrrolidine CAS 123-75-1 in stock
Product Information
Product Name: Pyrrolidine
Synonyms:TETRAMETHYLENEIMINE;pyrrolidine,tetrahydropyrrole;PYRROLIDINE,REAGENT;
TETRAHYDROPYRROLE(PYRROLIDINE);PYRROLIDINE 99+%;PYRROLIDINE, REDISTILLED, 99.5+%;
1-AZACYCLOPENTANE;AKOS BBS-00003603
CAS:123-75-1
MF:C4H9N
MW:71.12
EINECS:204-648-7
Product Categories:Building Blocks;C4 to C8;Aliphatics;Chemical Synthesis;Heterocyclic Building Blocks;Pyrrolidines;
Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines;Flavor;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;
123-75-1;bc0001;K00001
Mol File:123-75-1.mol
Pyrrolidine Chemical Properties
Melting point -63 °C
Boiling point 87-88 °C/760 mmHg (lit.)
density 0.852 g/mL at 25 °C (lit.)
vapor density 2.45 (vs air)
vapor pressure 128 mm Hg ( 39 °C)
refractive index n20/D 1.443(lit.)
FEMA 3523 | PYRROLIDINE
Fp 37 °F
storage temp. Store below +30°C.
solubility water: miscible
form Liquid
pka11.27(at 25℃)
color Colorless to Almost colorless
Odorat 0.10 % in propylene glycol. ammoniacal animal egg amine
PH12.9 (100g/l, H2O, 20℃)
explosive limit1.6-10.6%(V)
Odor Typeammoniacal
Water Solubility Miscible with alcohol, ether, chloroform and water.
Sensitive Air Sensitive
Merck 14,8015
JECFA Number1609
BRN 102395
Dielectric constant8.3000000000000007
Stability:Stable; flammable. Incompatible with strong acids, strong oxidizing agents.
InChIKeyRWRDLPDLKQPQOW-UHFFFAOYSA-N
LogP0.22 at 25℃
CAS DataBase Reference123-75-1(CAS DataBase Reference)
NIST Chemistry ReferencePyrrolidine(123-75-1)
EPA Substance Registry SystemPyrrolidine (123-75-1)
Uses
Pyrrolidine is a flammable alkaline liquid that undergoes reactions typical of secondary amines. It is used to prepare
pesticides and rubber accelerators and as a chemical intermediate (usually the hydrochloride form) in the pharmaceutical
industry. There is relatively limited industrial exposure to this material.
Application
Pyrrolidine is a heterocyclic compound used as a building block in the synthesis of wide range of pharmaceutical compounds,
namely matrix metalloprotein inhibitors (MMPIs) and aminopeptidase N inhibitors (APNIs). It has been used for the
synthesis of N-benzoyl pyrrolidine from benzaldehyde via oxidative amination. It may be used as a catalyst for the
synthesis of N-sulfinyl aldimines from carbonyl compounds and sulfonamides.
Pyrrolidine can also be used to synthesize:
Taddol-pyrrolidine phosphoramidite, a ligand for rhodium-catalyzed [2+2+2] cycloaddition of pentenyl isocyanate and
4- ethynylanisole.
H,4 PyrrolidineQuin-BAM (′PBAM′), a selective catalyst for the aza-Henry addition of nitroalkanes to aryl aldimines.
1,2,3,3a,4,9-Hexahydropyrrolo[2,1-b]quinazoline by reacting with o-aminobenzaldehyde.
Product Picture
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Packing:20kg/carton、22kg/carton、25kg/drum,etc
Shipping:by sea or by air
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Small quantity | Aluminium bag, inside two level plastic bags(1KG or less/Aluminium bag) |
Bulk quantity | 25kg/drum, inside two level plastic bags |
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Moisture-proof Plastic Bags Aluminum Foil Bag 5KG/10KG/25KG/45KG/180kg Drums |
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