Factory supply Allopurinol CAS 315-30-0 in stock
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Low price Allopurinol CAS 315-30-0 in stock
Low price Allopurinol CAS 315-30-0 in stock
Low price Allopurinol CAS 315-30-0 in stock
Product Information
Product Name: Allopurinol
Synonyms:Hydroxypyrazolodpyrimidine;pyrazolo(3,4-d)pyrimidin-1-ol;AllopurinolBp2001;
4-Oxopyrazolo[3,4-d]pyrimidine;NSC 101655;ALLOPURINOL,USP;
1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE(ALLOPURINOL);ALLOPURINOL(P)
CAS:315-30-0
MF:C5H4N4O
MW:136.11
EINECS:206-250-9
Product Categories:Miscellaneous Natural Products;Fused Ring Systems;Heterocyclic Compounds;Antitumors for Research
and Experimental Use;Chemical Reagents for Pharmacology Research;Biochemistry;PYRIMIDINE;Nucleobases and their
analogs;Nucleosides, Nucleotides & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;
API's;Other APIs;Miscellaneous Enzyme;Bases & Related Reagents;Nucleotides;ZYLOPRIM;inhibitor;315-30-0;john's
Mol File:315-30-0.mol
Allopurinol Chemical Properties
Melting point >300 °C (lit.)
Boiling point 250.36°C (rough estimate)
density 1.4295 (rough estimate)
refractive index 1.8500 (estimate)
storage temp. 15-25°C
solubility 1 M NaOH: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow
form Powder
pka10.2(at 25℃)
color White or almost white
Water Solubility 0.35 g/L (25 ºC)
Merck 14,279
BCS Class3,1
InChIKeyOFCNXPDARWKPPY-UHFFFAOYSA-N
CAS DataBase Reference315-30-0(CAS DataBase Reference)
NIST Chemistry ReferenceAllopurinol(315-30-0)
EPA Substance Registry SystemAllopurinol (315-30-0)
Uses
Xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout.
Antiurolithic
antihyperuricemia, antigout, antiurolithic
Allopurinol does not reduce serum uric acid levels by increasing renal uric acid excretion; instead it lowers plasma urate
levels by inhibiting the final steps in uric acid biosynthesis.
Uric acid in humans is formed primarily by xanthine oxidase-catalyzed oxidation of hypoxanthine and xanthine to uric acid.
Allopurinol (8) and its primary metabolite, alloxanthine (9) [CAS: 2465-59-0], are inhibitors of xanthine oxidase.
Inhibition of the last two steps in uric acid biosynthesis by blocking xanthine oxidase reduces the plasma concentration and
urinary excretion of uric acid and increases the plasma levels and renal excretion of the more soluble oxypurine precursors.
Normally, in humans the urinary purine content is almost solely uric acid; treatment with allopurinol results in the urinary
excretion of hypoxanthine, xanthine, and uric acid, each with its independent solubility. Lowering the uric acid
concentration in plasma below its limit of solubility facilitates the dissolution of uric acid deposits.
The effectiveness of allopurinol in the treatment of gout and hyperuricemia that results from hematogical disorders and
antineoplastic therapy has been demonstrated.
Product Picture
Packing & Shipping & Payment
Packing:20kg/carton、22kg/carton、25kg/drum，etc
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| Small quantity | Aluminium bag, inside two level plastic bags(1KG or less/Aluminium bag) |
| Bulk quantity | 25kg/drum, inside two level plastic bags |
| Others | can do your package or split small packages according to your request |
Moisture-proof Plastic Bags Aluminum Foil Bag 5KG/10KG/25KG/45KG/180kg Drums |
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